Parasitic Diseases List

[unable to retrieve full-text content] What is the importance of zoonotic trichomonads for human health?    ScienceDirect.com

Abstract Tuberculosis (TB) drug discovery and development has undergone nothing short of a revolution over the past 20 years. Successful public–private partnerships and sustained funding have delivered a much-improved understanding of mycobacterial disease biology and pharmacology and a healthy pipeline that can tolerate inevitable attrition. Preclinical and clinical development has evolved from decade-old concepts to adaptive designs that permit rapid evaluation of regimens that might greatly shorten treatment duration over the next decade. But the past 20 years also saw the rise of a fatal and difficult-to-cure lung disease caused by nontuberculous mycobacteria (NTM), for which the drug development pipeline is nearly empty. Here, we discuss the similarities and differences between TB and NTM lung diseases, compare the preclinical and clinical advances, and identify major knowledge gaps and areas of cross-fertilization. We argue that applying paradigms and networks that have proved su...

[unable to retrieve full-text content] Which larvae are they? Use of single larva for the molecular confirmation of Cooperia pectinata and Cooperia punctata ...    ScienceDirect.com

Hausermann H, Tschakert P, Smithwick EA, Ferring D, Amankwah R, Klutse E, et al. Contours of risk: spatializing human behaviors to understand disease dynamics in changing landscapes. EcoHealth. 2012;9(3):251–5. Article  PubMed  Google Scholar  Hosseini PR, Mills JN, Prieur-Richard AH, Ezenwa VO, Bailly X, Rizzoli A, et al. Does the impact of biodiversity differ between emerging and endemic pathogens? The need to separate the concepts of hazard and risk. Philos Trans R Soc Lond B Biol Sci. 2017;372(1722):20160129. Article  PubMed  PubMed Central  Google Scholar  Diuk-Wasser MA, VanAcker MC, Fernandez MP. Impact of land use changes and habitat fragmentation on the eco-epidemiology of tick-borne diseases. Reisen W, editor. J Med Entomol. 2021;58(4):1546–64. Article  PubMed  ...

[unable to retrieve full-text content] FDA Approves Biktarvy Label Update With Data for Use During Pregnancy    Infectious Disease Special Edition

One of the most common worms found in dogs is a tapeworm. Tapeworms are an intestinal parasite, meaning that they're inside of your dog's intestines. Along with roundworm, hookworm, and whipworm, this flat, segmented worm is found in dogs, cats, humans, and many other species around the world. Here's what you should know about tapeworms in dogs, including symptoms, diagnosis, and subsequent treatment. How Do Dogs Get Tapeworms? There is a cycle through which dogs get tapeworms. Unlike other parasites that dogs may get from exposure to an infected dog's feces, dogs can only get tapeworms by ingesting a host (most often an adult flea) that has tapeworm eggs inside it. There are a few ways a dog might ingest a flea, such as self-grooming, or grooming a dog or cat housemate. Other animals that can potentially transmit flea eggs include birds, rabbits, or rodents. Once digested, the tapeworm eggs settle into your dog's small intestine. There, t...

Abstract The black rat ( Rattus rattus ) is a globally invasive species that has been widely introduced across Africa. Within its invasive range in West Africa, R. rattus may compete with the native rodent Mastomys natalensis , the primary reservoir host of Lassa virus, a zoonotic pathogen that kills thousands annually. Here, we use rodent trapping data from Sierra Leone and Guinea to show that R. rattus presence reduces M. natalensis density within the human dwellings where Lassa virus exposure is most likely to occur. Further, we integrate infection data from M. natalensis to demonstrate that Lassa virus zoonotic spillover risk is lower at sites with R. rattus . While non-native species can have numerous negative effects on ecosystems, our results suggest that R. rattus invasion has the indirect benefit of decreasing zoonotic spillover of an endemic pathogen, with important implications for invasive species control across West Africa. ...