Parasitic Diseases List

Image: Shutterstock In This Article The American Academy of Pediatrics (AAP) advises administering a vitamin K shot at birth to newborns. Vitamin K is a vital fat-soluble vitamin crucial in maintaining various physiological functions, including blood clotting. The body stores the vitamin in the liver, brain, heart, pancreas, and bones, but these reserves are limited in newborns. Therefore, they are at an increased risk of vitamin K deficiency bleeding (VKDB), a rare but serious blood disorder that most often affects babies in the first days or weeks of life (1) (2) (3). Keep reading to learn more about the safety, significance, and possible side effects of the vitamin K shot for infants. Why Is Vitamin K Necessary For Newborn Babies? Image: Shutterstock Newborns are at risk of developing a bleeding disorder called vitamin K deficiency bleeding (VKDB) due to their low stores of vitamin K at birth.   This condition can lead to excessive bleeding or hemorrhage ...

If your child is scratching their head, neck and ears, they may have head lice. While lice aren't harmful, they can be a time consuming – and often embarrassing – pest. Read on to learn how to check for, treat and prevent head lice.    "Head lice are very common. About 6 to 12 million kids are treated for head lice in the United States each year, and lice are especially prevalent among school-aged children, their families and caretakers," says Michael Turco, MD, Clarkson Family Medicine resident. What are head lice, and how do they spread? Head lice are tiny, wingless insects that live on hair and feed on human blood. Their bites can irritate the scalp and, in some cases, lead to infection from constant scratching. They spread mostly through direct head-to-head contact and less frequently by sharing personal items, such as:  Hats and scarves  Brushes and hair accessories   Headphones  Pillows an...

A new study published in the International Journal of Molecular Sciences discusses the impact of herpes, influenza, hepatitis, human immunodeficiency virus (HIV), the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), and respiratory syncytial virus (RSV) viruses on blood-brain barrier (BBB) function and insulin sensitivity, as well as their underlying mechanisms. Study:  The Effects of Viruses on Insulin Sensitivity and Blood–Brain Barrier Function. Image Credit: Billion Photos / Shutterstock.com Viruses and DM HIV Previously, a diagnosis of acquired immunodeficiency syndrome (AIDS) was accompanied by a shortened life expectancy; however, medical advances have led to the development of effective treatments that have improved the quality of life and life expectancy of patients with AIDS. Nevertheless, as AIDS patients began to live longer, they became more likely to be diagnosed with lipodystrophy, metabolic syndrome, insulin resistance, hyperglyce...

Von Willebrand factor (VWF) is a protein that plays a key function in the early stages of blood clotting (haemostasis) Initially, Von Willebrand factor promotes the adhesion of platelets to damaged blood vessel walls and subsequently acts as a bridge between one platelet and another, acting as a glue and thus promoting clot formation. It also binds coagulation factor VIII, protecting it from degradation by protein-fragmenting enzymes (proteases). Deficiency of the factor results in a disease known as Von Willebrand Disease, the most frequent hereditary haemorrhagic disease. Von Willebrand Disease is classified into three main groups, based on the type of Von Willebrand factor deficiency: Type 1 is the most frequent form, characterised by a partial quantitative defect in Von Willebrand factor, usually resulting in mild to moderate bruising and bleeding; Type 2 is the form characterised by a defect in Von Willebrand factor function, which in turn is subdivided into fou...

[unable to retrieve full-text content] Von Willebrand Disease: Types, Symptoms, Treatments    Healthgrades

[unable to retrieve full-text content] AIM2 sensors mediate immunity to Plasmodium infection in ...    pnas.org

The R21/Matrix-M pre-erythrocytic malaria vaccine candidate was developed at the University of Oxford (Oxford, UK) and is currently manufactured by the Serum Institute of India (Pune, India). It is said that the colonising East India Company and later the British Crown lost more soldiers to the malaria epidemics in India's tropical climate than to war or battle here. As per the World Health Organisation report, India, along with four African countries, had 95 per cent of the entire Malaria infection in the world in 2018. 4,50,000 people died due to Malaria in 2018. But now, it is truly a Eureka moment as Rhys Blakely, Science Correspondent, The Times writes about how hopes have been lifted that millions of African children could be protected against malaria as soon as next year after a trial of a vaccine developed by Oxford University achieved "fantastic" results. Related News The Times cites a Lancet release that announces that the jab gave small children in Burkina Faso...

DEAR MAYO CLINIC: My 4-year-old daughter already has had three ear infections this winter. When she isn't feeling well, our entire family is miserable. The pediatrician says she may continue to get more infections and it is just her body. Why do some kids get ear infections so easily? And is there anything I can do to prevent the infections and help her feel better faster? ANSWER: Our ears — home to the smallest bones in the body — are amazing organs. They help us hear and experience the world. They also help maintain balance. They are self-cleaning, and the outer part of the ear never stops growing. Yet, as your family has discovered, ear infections can cause pain and discomfort. Infections can occur in the middle ear , in the air-filled space behind the eardrum that contains the tiny vibrating bones of the ear. Middle ear infections, which are the most common ear infections, are caused by a bacterium or virus that infects fl...

[unable to retrieve full-text content] What out for roundworm in your pets    WGME

ReportLinker The growth of the market is majorly driven by the increasing prevalence of blood disorders and the rising incidence of cardiovascular diseases. However, the high costs and stringent regulations associated with coagulation analysers hamper the market growth. New York, Jan. 19, 2023 (GLOBE NEWSWIRE) -- Reportlinker.com announces the release of the report "Coagulation Analyzer Market Forecast to 2028 - COVID-19 Impact and Global Analysis By Product, Test, Technology, and End Users" - https://www.reportlinker.com/p06382128/?utm_source=GNW Increasing Prevalence of Blood Disorders Coagulation analyser device measures and evaluates the speed of clot formation or clot coagulation.It provides a fast and simple way to accurately measure the levels of blood platelet, thrombolin, and thromboplastin. According to the National Organizations of Rare Disorders, hemophilia A is a common X-linked recessive disorder and the second most common inherited clotting factor deficiency af...

Abstract School-based mass drug administration (MDA) of Praziquantel (PZQ) is the global intervention strategy for elimination of schistosomiasis. Genetic variations in drug metabolizing enzymes and transporter proteins influences drug exposure and treatment outcomes, but data on PZQ pharmacokinetics and safety outcomes are scarce. We investigated the effect of pharmacogenetics variations on PZQ plasma concentrations and safety outcomes among 462 Rwandan schoolchildren who received single dose PZQ and albendazole in MDA. Genotyping for common functional variant alleles CYP3A4*1B , CYP3A5 (*3, *6, *7), CYP2C19 (*2, *3, *17), CYP2C9 (*2, *3) and CYP2J2*7 were done. Plasma concentration of PZQ, cis -4-OH-PZQ and trans -4-OH-PZQ were measured using LC/MS/MS. Active safety monitoring was done on days 1, 2, and 7 post-MDA. CYP2C9 and CYP2C19 genotypes were significantly associated with PZQ plasma concentrations and its cis - and trans -4-OH-PZQ/PZQ metabolic ratios (MR). CYP2C9*2 and ...