Parasitic Diseases List

Objective: The study aimed to evaluate the causes of thrombocytopenia in pregnancy and its management along with the outcome in the COVID-19 era. Methods: Recruitment for this prospective, cross-sectional observational study of thrombocytopenia in pregnancy (platelet counts <100x10 9 /L) was done from January 2017 to August 2020 at the National Institute of Blood Diseases (NIBD) after taking the patients' informed consent. Complete clinical and lab profile of patients was also collected. Results: A total of 150 pregnant women with thrombocytopenia were enrolled, with the mean age being 27.3±4.64 years. Mean platelet counts at baseline were 48.0±24. Main clinical manifestations at baseline included: anemia 65.9%, bruises 23.25%, and edema 9.3%. Causes of thrombocytopenia were gestational thrombocytopenia (GT) 72 (48%), acute fatty liver five (3.3%), pre-eclampsia in 11 (7.3%), and eclampsia seven (4.6%). Causes not specific to pregnancy included 30 (20%) cases ...

The nonprofit Companion Animal Parasite Council (CAPC) — the nation's leading source on parasitic diseases that threaten the health of pets and people — released its annual 2022 Pet Parasite Forecast. CAPC's 2022 Pet Parasite Forecast is critical to alerting pet owners to the risks this year and reinforcing CAPC's recommendation that all pets need to be annually tested and protected year-round. SALEM, Ore. (PRWEB) February 27, 2022 The nonprofit Companion Animal Parasite Council (CAPC) — the nation's leading source on parasitic diseases that threaten the health of pets and people — today released its annual 2022 Pet Parasite Forecast. CAPC's 2022 forecast warns that vector-borne diseases — heartworm, Lyme, ehrlichiosis and anaplasmosis – will all pose...

The immune system deteriorates with age, making COVID-19 particularly deadly in older people -; but to date, no clinically available medication addresses this key risk factor. A study published today in Nature shows that an oral drug that reverses multiple aspects of immune aging effectively prevents death in a mouse model of COVID-19, suggesting that the medication could be used to protect the elderly patients who are at greatest risk in the pandemic. In the study, daily doses of BGE-175 (asapiprant) protected aged mice from a lethal dose of SARS-CoV-2, the virus that causes COVID-19. Ninety percent of mice that received the drug survived, whereas all untreated control mice died. BGE-175 treatment was initiated two days after infection, when the mice were already ill, a time-frame relevant to real-life clinical situations in which patients would receive medication only after becoming symptomatic. The mouse model used in the study closely mirrored the pathological progression ...

Design and setting of the study Our study area was a small rural town of Ingwavuma, located in northern KwaZulu-Natal province of South Africa, close to the borders of eSwatini (in the north) and Mozambique (in the east). Ingwavuma is under traditional authority and is regarded as the worst poverty-stricken area in KwaZulu-Natal with an estimated annual income of R32 812 ([19] p. 17). Most people in this area depend heavily on social grants estimated to R13 090 per annum (less than $1000) as their main source of income [19]. The prevalence of Schistosoma haematobium among school aged children (over 10 years) in Ingwavuma is 37.5%. However, among the 1–5 years age group prevalence for both S. mansoni and S. haematobium is 2% [20]. The risk factors for schistosomiasis among young children include the caregiver's age, type of household head, poor sanitation, access to water source and knowledge about schistosomiasis [21]. The study was an analytical cohor...

Imagine a cure that's as contagious as the disease it fights—a vaccine that could replicate in a host's body and spread to others nearby, quickly and easily protecting a whole population from microbial attacks. That's the goal of several teams around the world who are reviving controversial research to develop self-spreading vaccines. Their hope is to reduce infectious disease transmission among wild animals, thereby lowering the risk that harmful viruses and bacteria can jump from wildlife to humans as many experts believe happened with SARS-CoV-2, the virus that caused the COVID-19 pandemic. The U.S. Centers for Disease Control and Prevention estimates that 60 percent of all known infectious diseases and 75 percent of new or emerging infectious diseases are zoonotic. Scientists cannot predict why, when, or how new zoonotic diseases will emerge. But when they do, these diseases are often deadly and costly to control. What's more, many researchers predict that climate c...

Congenital hemophilia A (factor VIII deficiency) is a bleeding disorder that results from pathologic variants in the gene F8 on the X chromosome. Among persons with hemophilia, those with severe disease (i.e., a factor VIII activity level of <1%) have the highest risk of spontaneous and traumatic life- and limb-threatening bleeding. 1 Poorly controlled hemophilia manifests with chronic arthropathy associated with pain, decreased mobility, and a restricted lifestyle. To correct the coagulation defect and ameliorate bleeding, the factor VIII protein or function must be restored. The standard of care for severe hemophilia A is the prevention of bleeding with regular prophylactic . . . Adblock test (Why?)

Furuncles (boils) and carbuncles (clusters of boils) are lesions that form on the skin around a hair follicle. Since these growths look similar, some people use both terms interchangeably. Yet, furuncles and carbuncles aren't exactly the same. This article will explain differences between the two types of lesions, as well as explore their similarities, causes, and complications. The main difference is that a furuncle is one boil on the skin, whereas a carbuncle is a cluster or collection of boils. Carbuncles form when an infection travels deeper within the skin. These lesions are similar in that they produce pus-filled lumps, and they also appear on similar parts of the body. This includes areas with hair and friction. Some people get furuncles and carbuncles on the back of their neck, under their arms, on their thighs, or in the groin area. Other than the number of lesions on the skin, furuncles and carbuncles have specific characteristics that set them apart. Symptoms of furuncle...

Abstract The genes of the major histocompatibility complex (MHC) are an essential component of the vertebrate immune system and MHC genotypes may determine individual susceptibility to parasite infection. In the wild, selection that favors MHC variability can create situations in which interspecies hybrids experience a survival advantage. In a wild system of two naturally hybridizing leuciscid fish, we assessed MHC IIB genetic variability and its potential relationships to hosts' ectoparasite communities. High proportions of MHC alleles and parasites were species-specific. Strong positive selection at specific MHC codons was detected in both species and hybrids. MHC allele expression in hybrids was slightly biased towards the maternal species. Controlling for a strong seasonal effect on parasite communities, we found no clear associations between host-specific parasites and MHC alleles or MHC supertypes. Hybrids shared more MHC alleles with the more MHC-diverse parental species, bu...