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Mental health concerns during the COVID-19 pandemic as revealed by helpline calls - Nature.com

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Abstract Mental health is an important component of public health, especially in times of crisis. However, monitoring public mental health is difficult because data are often patchy and low-frequency 1,2,3 . Here we complement established approaches by using data from helplines, which offer a real-time measure of 'revealed' distress and mental health concerns across a range of topics 4,5,6,7,8,9 . We collected data on 8 million calls from 19 countries, focusing on the COVID-19 crisis. Call volumes peaked six weeks after the initial outbreak, at 35% above pre-pandemic levels. The increase was driven mainly by fear (including fear of infection), loneliness and, later in the pandemic, concerns about physical health. Relationship issues, economic problems, violence and suicidal ideation, however, were less prevalent than before the pandemic. This pattern was apparent both during the first wave and during subsequent COVID-19 waves. Issues linked directly to the pandemic the...

Misdiagnosis of von Willebrand disease | JBM - Dove Medical Press

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Introduction von Willebrand disease (VWD) is the most common inherited bleeding disorder. 1,2 Despite this, VWD is one of the most commonly misdiagnosed or overlooked entities in everyday clinical practice. Of interest, VWD may be both over- and under-diagnosed, as well as misdiagnosed, either as another entity or as a different subtype of the disorder. This review will detail the causes underlying the diagnostic uncertainties overshadowing VWD and provide solutions on how to overcome these. von Willebrand Disease VWD was first described by Finnish physician Erik Adolf von Willebrand in 1926, following the presentation of a young girl with recurrent episodes of bleeding, which were clinically distinct from haemophilia. 3 VWD is caused by quantitative or qualitative deficiencies in a plasma protein now called von Willebrand factor (VWF). VWF is a large, complex protein that has essential roles in primary and secondary hemostasis. 4 High-molecular-weight VWF multimers mediate ...

Mind-controlling fungus could cause more crop damage in warmer climates - The Natural History Museum

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Dead heat  For the new study, aphids and ladybirds were separated into separate groups, with one group remaining healthy while the others were infected with either a small or large amount of Beauveria bassiana spores. The researchers then tested the temperature at which the insects were unable to flip themselves over as a measure of their heat tolerance.  Dr Mitzy Porras, the lead author of the study, says, 'We found that the heat tolerance of fungus-infected aphids and beetles was reduced by 6.7⁰C and 4.5⁰C respectively while cold tolerance was only reduced in the beetles.  'In addition, survival was significantly reduced for infected aphids and beetles when they were exposed to both warm and cold extreme temperatures.'  The researchers suggest that the fungus is blocking a process known as behavioural fevering to help with its own survival. Behavioural fevering is when infected insects move into warmer temperatures to weaken th...

Gumboro Prevention: all you need to know about Infectious Bursal Disease - The Poultry Site

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HIPRA enter a new era in the prevention of Gumboro disease in poultry with the launch of a new microsite : www.gumboroprevention.com All you need to know about Infectious Bursal Disease As one of the leading companies in vaccines against Gumboro disease , HIPRA has decided to make its knowledge available to all those interested in this subject through a new microsite devoted entirely to improving the prevention of the disease . Infectious bursal disease is one of the major infectious diseases in the poultry sector, with a worldwide distribution and a high economic impact due to its immunosuppressive effect. Despite the efforts to combat the disease that have been undertaken over the last 50 years, the unstoppable evolution of the Gumboro virus has not allowed us to lower our guard and has required the application of new control strategies . The main objective of this microsite is to share updated information, with all professionals in the sector, for continuous impr...