Parasitic Diseases List

Bleeding disorders affect the way the body controls blood clotting. If your blood does not clot enough, you may experience problems with bleeding too much after an injury or surgery. Blood that clots too much can lead to other medical conditions, such as thrombotic disorders. This health topic focuses on bleeding disorders that are caused by problems with clotting factors, including hemophilia and von Willebrand disease. Clotting factors, also called coagulation factors, are proteins in the blood that work with small cells, called platelets, to form blood clots. Any problem that affects the function or number of clotting factors or platelets can lead to a bleeding disorder. A bleeding disorder can be inherited, meaning that you are born with the disorder, or it can be acquired, meaning it develops during your life. Symptoms can include easy bruising, heavy menstrual periods, and nosebleeds that happen often. To diagnose your bleeding disorder, your healthcare provider may need ...

Overview COVID-19, also called coronavirus disease 2019, is an illness caused by a virus. The virus is called severe acute respiratory syndrome coronavirus 2, or more commonly, SARS-CoV-2. It started spreading at the end of 2019 and became a pandemic disease in 2020. Coronavirus Enlarge image Close Coronavirus Coronavirus Coronaviruses are a family of viruses. These viruses cause illnesses such as the common cold, severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS) and coronavirus disease 2019 (COVID-19). The virus that causes COVID-19 spreads most commonly through the air in tiny droplets of fluid between people in close contact. Many people with COVID-19 have no symptoms or mild illness. But for older adults and pe...

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Reviews Chevron icon It indicates an expandable section or menu, or sometimes previous / next navigation options. Pets The 5 best cat dewormers of 2024 Written by Jackie Brown ; edited by Lisa Sabatini Updated 2024-02-20T19:05:06Z This article was medically reviewed by Karie Johnson, DVM, a veterinarian in the south suburbs of Chicago whose focus is on nutrition, osteoarthritis, behavior, and end-of-life care. She is published in the Journal of the American Veterinary Association. Medically Reviewed Reviewed By Check Mark Icon A check mark. It indicates that the relevant content has been reviewed and verified by an expert Our stories are reviewed by medical professionals to ensure you get the most accurate and useful information about your health and wellness. For more information, visit our medical review board. Angle down icon An icon in the shape of an angle pointing down. The best cat dewormers come in two mai...

Abstract Sexual reproduction of Toxoplasma gondii , confined to the felid gut, remains largely uncharted owing to ethical concerns regarding the use of cats as model organisms. Chromatin modifiers dictate the developmental fate of the parasite during its multistage life cycle, but their targeting to stage-specific cistromes is poorly described 1,2 . Here we found that the transcription factors AP2XII-1 and AP2XI-2 operate during the tachyzoite stage, a hallmark of acute toxoplasmosis, to silence genes necessary for merozoites, a developmental stage critical for subsequent sexual commitment and transmission to the next host, including humans. Their conditional and simultaneous depletion leads to a marked change in the transcriptional program, promoting a full transition from tachyzoites to merozoites. These in vitro-cultured pre-gametes have unique protein markers and undergo typical asexual endopolygenic division cycles. In tachyzoites, AP2XII-1 and AP2XI-2 bind DNA as heterodimers at ...