Parasitic Diseases List

The dispersion of respiratory droplets when walking behind a person going downstairs carries an increased risk for infection compared with those generated when walking behind a person going upstairs, according to results of a study published in AIP Advances . Investigators used a laboratory water tunnel experiment to study the dispersion of respiratory droplets exhaled from a person going up- or downstairs. To mimic a person going up- or downstairs, a human-shaped manikin with a height of 9 cm was placed 27 cm downstream from the inlet of the test section. The investigators used inclination angles of 60 ° , 90 ° , and 120 ° to simulate a person going downstairs, walking on flat ground, and going upstairs, respectively. The median diameter of particles used in the experiment to mimic virus-containing respiratory droplets from sneezing and coughing was 0.007 mm; the mean ejection speed was 33 cm/s. Investigators carried out flow visualization of the particle dispersion u...

A new moose research project is in progress in the Adirondack region. This winter, 14 moose were fitted with GPS collars as part of a multi-year project assessing moose health and population. Data collected from the collars will guide research on moose population, health, mortality and dispersal. To safely capture, collar and monitor these animals, DEC has partnered with researchers at the New York Cooperative Fish and Wildlife Research Unit and the College of Veterinary Medicine at Cornell University, the State University of New York College of Environmental Science and Forestry (SUNY ESF), and Native Range Capture Services. "New York's storied moose population, which began its recovery in the 1980s, is a critical part of our state's biodiversity," according to Commissioner Basil Seggos. Additional moose will be equipped with GPS collars in years to come to provide location data and information on moose activity patterns, movements and mortality. Data collected du...

Despite some differences, "it's heartening that for the most part there's concordance," says Bernard Prendergast. Strategies for surgery to treat left-sided infective endocarditis (IE) differ between the US and Europe, in large part because the evidence base is limited, according to a new review that compares guidelines from the two regions. The paper, published recently in the European Heart Journal , "exposes areas of uncertainty and gaps in current evidence for the use of surgery in IE across different indications, particularly related to its timing and consideration of operative risk," write co-authors Andrew Wang, MD (Duke University Medical Center, Durham, NC), and Emil L. Fosbøl, MD, PhD (University Hospital of Copenhagen, Rigshospitalet, Denmark). The latest guidelines to mention the topic were two 2021 documents on the management of valvular heart disease as a whole: one from the American College of Cardiology and American Heart ...

Healthy fingernails are smooth and appear in different colors as they grow out. But they're actually transparent. Fingernails can look white at the base, pink on the majority of the nail, and white or clear at the tip. Discoloration or changes to the texture of your nail may be signs of certain environmental factors, injuries, or medical conditions. Not all changes to fingernails are a medical concern. Fingernails are made of the protein keratin and flattened cells. The nail plate, or the top part of the nail, is transparent, or clear, because the flattened cells don't have nuclei. The nail appears to be different colors because the clear nail exposes colors underneath the nail plate, including: Lunula. This is the half-moon white shape at the bottom of your nail (you may not see this on every nail). One reason it appears white is because your skin is thicker at the bottom of the nail. Nail bed. This is under your nail plate and is pink in color. This is pink because the skin...

This article was originally published here PLoS Negl Trop Dis. 2022 Jan 24;16(1):e0010151. doi: 10.1371/journal.pntd.0010151. Online ahead of print. ABSTRACT Schistosoma haematobium is the leading cause of urogenital schistosomiasis and it is recognised as a class 1 carcinogen due to the robust association of infection with bladder cancer. In schistosomes, tetraspanins (TSPs) are abundantly present in different parasite proteomes and could be potential diagnostic candidates due to their accessibility to the host immune system. The large extracellular loops of six TSPs from the secretome (including the soluble excretory/secretory products, tegument and extracellular vesicles) of S. haematobium (Sh-TSP-2, Sh-TSP-4, Sh-TSP-5, Sh-TSP-6, Sh-TSP-18 and Sh-TSP-23) were expressed in a bacterial expression system and polyclonal antibodies were raised to the recombinant proteins to confirm the anatomical sites of expression within the parasite. Sh-TSP-2, and Sh-TSP-18 were identifi...

Enhanced AP-PA02 enters SWARM-P.a. study AP-PA02 identified as lead cocktail for non-cystic fibrosis bronchiectasis Phase 2 trial Distinct phage cocktail (AP-PA03) for pneumonia advances to manufacturing MARINA DEL REY, Calif. , Jan. 5, 2022 /PRNewswire/ -- Armata Pharmaceuticals, Inc. (NYSE American: ARMP) ("Armata," "us," "our," or the "Company"), a biotechnology company focused on pathogen-specific bacteriophage therapeutics for antibiotic-resistant and difficult-to-treat bacterial infections, today announces the modification of its lead bacteriophage product candidate, AP-PA02, to include additional phage genera that increase potency and broaden coverage of strains of Pseudomonas aeruginosa found in patients with cystic fibrosis (CF) and non-cystic fibrosis bronchiectasis (NCFB). Armata Pharmaceuticals Logo (PRNewsfoto/Armata Pharmaceuticals, Inc.) The improvements in AP-PA02 reflect Armata's core strategy of utilizing clinical isolate ...

Pottawatomie County has seen its first documented kissing bug specimen, according to a recent Facebook post from the Pottawatomie County OSU Extension Office. "This insect can carry a tropical disease and is being tracked in many states, including Oklahoma and Texas," the post said. Carla Smith, horticulture educator with the Pottawatomie County office, said the bug is on a watch list. "Not all of the insects will necessarily be a carrier, but it's something we need to monitor," she said. Smith said a client who lives in northeast Pottawatomie County in the North Rock Creek area found one of the bugs and recognized it from something he'd seen and took it into the extension office around the end of August. "This is the first one our office has accepted as a sample and has dealt with," she said. The sample the area resident collected will be sent off for testing to see if it is a carrier for Chagas disease. If anyone sees a bug they think might be a ...

First, it appeared as a tiny blemish under the eye. But over the next two weeks, the 32-year-old woman watched it move — snapping photos as it formed bumps above her eye before it made its way down into her lip, forcing her mouth to swell. It was a parasite — and it was living inside her face. The case — and shocking images — were published Thursday in a report titled " Migrating  Dirofilaria repens"  in the New England Journal of Medicine, detailing a case in which a woman from Russia became host to a parasite through a mosquito bite. The report states the woman, who was not named, started showing symptoms after traveling to a rural area not far from Moscow, where she "recalled being frequently bitten by mosquitoes." She experienced only occasional itching and burning as the worm slithered under her skin. Dirofilaria are usually found in dogs or othe...

26 January 2022 Take a second and count to two. By now, someone in the United States needs blood. Yes, whether it's for cancer patients or an organ transplant, someone needs a transfusion every two seconds. In today's world, many things can be manufactured in a plant or research lab. Unfortunately, blood transfusions in hospitals are only possible thanks to donor blood.  Each year, nearly 7 million Americans donate blood. The downside is that it amounts to only 3 percent of age-eligible people. Donating blood goes a long way, especially during the pandemic. Recently, the Red Cross said it's experiencing the worst blood shortage in over a decade. This blog serves as a reminder of how a single donation can save someone's life. Types of blood donation Blood contains red blood cells, platelets and plasma. There are...

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1 INTRODUCTION By the end of April 2021, there were several case reports of thrombosis with thrombocytopenia after receiving the first dose of the ChAdOx1 nCoV-19 vaccine. Most cases presented with thrombosis at unusual sites. 1-3 In addition, anti–platelet factor 4 (PF4)/polyanionic antibodies were positive in almost all patients. This resulted in many countries halting coronavirus disease 2019 (COVID-19) vaccination with ChAdOx1 nCoV-19. While many countries resumed the vaccination after their regulators suggested that the benefits of the vaccine outweighed the risk of thrombosis, several countries have restricted the vaccine to older populations, such as those aged >50 years. In Asia, Thailand, Taiwan, Malaysia, and South Korea have resumed inoculation. To date, the occurrences of VITT have been mostly reported in White persons, 4 while data in Asia have been sparsely reported. In Thailand, where about 15 million...