Parasitic Diseases List

SOUTH SAN FRANCISCO, Calif.--( BUSINESS WIRE )--Genentech, a member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY), today announced results from an interim analysis of the Phase III HAVEN 6 study, which show Hemlibra ® (emicizumab-kxwh) demonstrated a favorable safety profile and effective bleed control in people with moderate or mild hemophilia A without factor VIII inhibitors. The data were presented at the 63rd American Society of Hematology (ASH) Annual Meeting and Exposition as an oral presentation on December 12, 2021. While the treatment and management of severe hemophilia A are well established, there is less information and treatment guidance on moderate and mild hemophilia A, which can lead to delayed or missed diagnoses of bleeding episodes. Considering this population may not use preventative treatments, these patients may experience worsened clinical burden, with less than 30% of people with moderate or mild hemophilia A living a bleed-free life. "We are p...

Despite pandemic-related disruptions, a total of 76.9 million people received treatment for schistosomiasis in 2020, representing a global coverage of 31.9%, compared with 105 million treated in 2019 (coverage of 44.8%). The latest data published by the World Health Organization (WHO) show that 28.6 million fewer people were treated for schistosomiasis (bilharzia) in 2020 than in 2019. This 27% drop in the number of treatments delivered is largely due to the implementation of COVID-19 measures, including school closures. "We commend the work of national programmes that were able to conduct treatment by observing COVID-19 safety protocols," said Dr Amadou Garba-Djirmay, Medical Officer, WHO Department of Control of Neglected Tropical Diseases, who heads the global schistosomiasis elimination programme . "Most interestingly, more than 90% of all treatment was delivered in countries of WHO's Africa Region, which carries the greatest global burden of schistosomiasis....

Gerry McCartney , professor 13, Margaret Douglas , lecturer 23, Martin Taulbut , public health information manager 3, S Vittal Katikireddi , professor 34, Martin McKee , professor 5 1 College of Social Sciences, University of Glasgow, Glasgow, UK 2 Usher Institute, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, UK 3 Public Health Scotland, Glasgow, UK 4 MRC/CSO Social and Public Health Sciences Unit, University of Glasgow, Glasgow, UK 5 Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, UK Correspondence to: G McCartney Gerard.McCartney{at}glasgow.ac.uk Gerry McCartney and colleagues argue for a new model of equitable, holistic, and sustainable public health should be central to recovery plans No amount of positive spin can detract from the numbers. The UK has not done well in the pandemic, whether measured in terms of mortality,1 economic performance,2 or social protection. This should not have ...

Gastritis and gastroenteritis may have similar names, but they are different health conditions. Gastritis tends to affect the lining of the stomach, whereas gastroenteritis affects the intestines. Gastritis is inflammation, or irritation, of the stomach lining. Gastroenteritis, on the other hand, is inflammation of the intestine, or the stomach and the bowel. Gastritis can be acute or chronic. The symptoms of acute gastritis come on suddenly and tend to go away on their own. Chronic gastritis comes on gradually and may require medical treatment. Gastroenteritis is a short-term condition that will usually resolve on its own. People sometimes call it stomach flu. This article will explain the key differences between the two conditions, what causes them, and their main symptoms. It will also look at treatments and prevention and when to consult a doctor. Gastritis and gastroenteritis are two separate conditions with different causes and symptoms, and they affect different parts of the di...

A chronic bacterial infection, a flame retardant, and six water disinfection byproducts are listed in a new HHS cancer report. Eight substances have been added to the Report on Carcinogens, bringing the total list to 256 substances that are known, or reasonably anticipated, to cause cancer in humans. This is the 15th Report on Carcinogens , which is a cumulative report, mandated by Congress and prepared by the National Toxicology Program (NTP) for the Secretary of the U.S. Department of Health and Human Services. The release of this report coincides with the 50th Anniversary of the National Cancer Act of 1971 , which initiated the nation's war on canc...

Background Identification of the infecting organism is essential for the diagnosis and treatment of infections, but detection rates from different kinds of culture samples are not necessarily good. 1 Particularly in sepsis patients, the detection rate from blood cultures is reportedly around 10–50%, although the detection of bacteria by blood culture takes 2–3 days. The reasons for such low detection rates include transience of the bacteremia or the fact that antibiotics have already been started at the time the sample is taken. Repeating two sets of blood cultures is always recommended, but various rapid tests that support the conventional culture methods have been devised. 2 Recently, some novel pathogen-identifying systems based on genetic and proteomic methods, such as next-generation sequencing (NGS) and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), have been developed. 3–5 These methods could detect the pathogenic bacteria an...

Dr. Keith Roach DEAR DR. ROACH: I am 68, and in fairly good health other than severe hemophilia A. When I experience a bleed, a painful and expensive hospital stay is usually required to receive treatment. With the flu and COVID-19 vaccines I've gotten, the bleeds were awful, but worth the risk. I am hesitant to get a colonoscopy now. I'd like to know your thoughts on colonoscopy, as I'm really scared about a puncture, and they can't safely remove something. I have zero clotting factor with inhibitors. A scratch will bleed for seven days with my meds. I carry bandages and gauze in my purse. I love my doctors, but they don't understand my fears. Am I right to hesitate? — C.G. ANSWER: Hemophilia A is a bleeding disorder caused by the lack of blood clotting factor VIII. It is most often an inherited condition, almost exclusively found in males, as it is sex-linked, but can be found in both men and women. People with blood clotting factor deficiencies are at risk for...

Colds and influenza can have similar presentations, with both making patients feel miserable, but there are key differences that pharmacists can help identify. Colds produce gradual symptoms, with slight aches, some fatigue and weakness, mild to moderate chest discomfort and cough, sneezing, sore throat, and stuffiness, but no chills, fever, or headache. Influenza, on the other hand, produces abrupt symptoms, usually including aches, chest discomfort, chills, cough, fatigue, fever, headaches, some congestion and sneezing, and weakness. Cold symptoms may last 3 to 10 days, whereas influenza symptoms may last 7 to 14 days and can even linger for up to 3 weeks. Generally, having influenza is worse than having a cold, and a cold will not result in other serious health conditions. But influenza can lead to bacterial infections, pneumonia, and even hospitalization. 1 The CDC estimates that in the United States between 2010 and 2020, influenza has resulted in around 9 to 41 million illnesses,...

In a Phase 1/2 dose-finding study called B-AMAZE, FLT180a gene therapy from Freeline Therapeutics brought about sustained levels of factor IX, the clotting factor that is missing in people with hemophilia B, and this translated into fewer bleeds each year. Levels of factor IX within the normal range were achieved with relatively low doses of FLT180a and maintained for more than three years. The results of the study, " Factor IX Expression within the Normal Range Prevents Spontaneous Bleeds Requiring Treatment Following FLT180a Gene Therapy in Patients with Severe Hemophilia B: Long-Term Follow-Up Study of the B-Amaze Program ," were presented in a poster at the 63rd American Society of Hematology (ASH) Annual Meeting and Exposition. The meeting was held on Dec. 11–14 at the Georgia World Congress Center in Atlanta. Recommended Reading "The data presented today at ASH demonstrate that FLT180a gene therap...

Roseola infantum is an infection caused by a type of herpes virus. It typically affects babies and toddlers. Other names for this health issue are sixth disease, exanthema subitum, or just "roseola." Around 90% of roseola cases occur before 2 years of age. This article summarizes how to identify roseola and how to tell the difference between this illness and measles. It also examines whether treatment is necessary. Roseola usually affects toddlers and babies under 2 years old . They may also have or show: general discomfort irritability an unwillingness to eat diarrhea a cough swelling or redness around the eyes ear pain swollen glands Roseola has a distinctive progression : A high fever develops, possibly suddenly, and may last for 3–5 days. A distinctive rash appears, usually on the torso, as the fever ends. The rash may progress to the neck, face, and limbs within 12–24 hours. The rash disappears after 1–2 days. The roseola rash may look like small pink spots or bumps tha...