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Von Willebrand Disease: Types, Symptoms, Causes, Diagnosis, Treatment and More - Health.com

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Von Willebrand disease (VWD) is the most common inherited bleeding disorder. The condition gets its name after Erik von Willebrand—a doctor who identified the disease in the 1920s. Your blood contains many proteins that help it clot properly and prevent excess blood loss. One of these proteins is called the "von Willebrand factor." This protein helps bind and clump with blood platelets, which are cell fragments in the blood that also help with clotting. When von Willebrand factor is present in your blood at low levels or if it's not working properly, you can experience heavy and frequent bleeding, like nosebleeds or abnormal menstrual bleeding. However, there are effective treatments available to manage the condition—and people who receive treatment can have healthy and active lives. There are four types of VWD and knowing what type you have is important. That's because each type has its own prognosis (outlook) and treatment plan. The types of VW

A Novel TLR4-Binding Domain of Peroxiredoxin From Entamoeba histolytica Triggers NLRP3 Inflammasome Activation ... - Frontiers

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Introduction Human amoebic colitis and amoebic liver abscess (ALA) are caused by the protozoan parasite Entamoeba histolytica , which is estimated to affect 50 million individuals and lead to 40,000–100,000 deaths annually (1). Macrophages are crucial for resisting E. histolytica trophozoite from invading host tissues and organs. Studies based on animal models have indicated that ALA formation predominantly depends on the innate immune response of the host (2). Adequate responses induce the generation of large quantities of reactive oxygen species (ROS) and other effector molecules to eliminate E. histolytica , while inadequate responses give rise to ALA formation (2). As nitric oxide (NO), synthesized by inducible NO synthase (iNOS), is paramount in macrophage-mediated amoeba elimination, mice with iNOS deficiency were prone to ALA formation and hepatocyte apoptosis (3). Inflammasome activation is one of the first innate immune events occurring during the host's immune responses

Rashes After Fever In Toddlers: Causes & Tips To Manage It - MomJunction

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Image: ShutterStock Fever and skin rashes can be present in many infectious diseases, and it is more common in children than adults. Despite the rashes, a toddler may appear well. These rashes can be due to immune reactions of the body towards the virus or other pathogen. A skin rash during fever can be more serious than a rash developing after fever. Sometimes bleeding spots may be confused with rashes. Read this post to learn about the various infectious diseases that cause skin rashes in toddlers after a fever. Causes Of Rashes After Fever In Toddlers Dr. Loretta Cody, a board-certified pediatrician from New York City Metropolitan Area, says, "Many viral illnesses in children can be associated with a rash. This is called a viral exanthem. Some of the common viral illnesses associated with a rash in toddlers are coxsackie, chickenpox, erythema infectiosum also known as Fifth disease, and roseola. The viral rashes can appear from red bumps and blotches to itchy fluid-filled blis

Islam Makhachev Reveals the Truth Behind Staph Infection Accusations Ahead of Dustin Poirier Fight at UFC 302 - EssentiallySports

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UFC lightweight champion Islam Makhachev is up and ready for UFC 302. Gearing up to defend his title against Dustin Poirier at UFC 302 on Saturday, the Dagestani was asked about the rumors of a staph infection ahead of the big day. Speculations that the champ may be suffering from a staph infection arose when the promotional pictures for the Prudential Center, Newark, New Jersey card showed a strange mark on his knee, which many, including Conor McGregor , felt was a sign that Makhachev is suffering from the skin condition and is not one hundred percent going into the bout. The Irishman took to Twitter and reacted to a picture in a now-deleted tweet, calling out Makhachev and his team for their alleged lapses in the best practices as far as hygiene is concerned. 'Notorious' suggested that the alleged infection could have been avoided if they had been following those best practices. ADVERTISEMENT Article continues below this ad However, Makhachev, on being asked about in the p

APIC Launches PolicyPro for Infection Control and Prevention - Infection Control Today

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Infection preventionists (IPs) have often struggled to write policies for their facilities. Sending hours to create and update policies that follow federal and state guidelines for their facilities, IPs need a resource where they can go to get already-written policies and get back to the work they need to do—fight infections. Recently, the Association for Professionals in Infection Control and Epidemiology (APIC), at the 2024 Annual Conference & Exposition held June 3 to 5 in San Antonio, Texas, announced the launch of PolicyPro. It is an infection control and prevention (IPC) policy library and management system of policies. Created by APIC's IP experts, this subscription-based management platform will allow health care organizations to adopt, manage, and customize IPC policies based on tried-and-true evidence. Currently available for acute care and hospital policies, PolicyPro's policies for long-term care and ambulatory will be available in late 2024 and 202

Best Online MPH Programs Of 2024 – Forbes Advisor - Forbes

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Consider Your Future Goals A versatile degree, the MPH lends itself to careers in multiple sectors. Graduates can become epidemiologists, enter the healthcare administration field, work in public policy or provide community education. With such a wide variety of job options for MPH graduates, you can find online MPH programs with concentrations or electives in nearly any professional specialization. You can also look for public health dual-degree programs, which pair the MPH with a second graduate credential in a field like social work, business, law or nursing. If you plan to start your job hunt directly after graduation, consider your work experience level. Many MPH programs include experiential learning opportunities like practicums or internships, but these components vary in length. If you already have a professional background in public health, you may not need extensive real-world practice, but if you're new to the field, a lengthier practicum or an internship can hel

Rat Lungworm: Causes and How It Spreads | Rat Lungworm Disease (Angiostrongylus) - CDC

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Causes Angiostrongylus cantonensis Angiostrongylus cantonensis , also known as the rat lungworm, is a parasitic nematode (worm) that is transmitted between rats and mollusks (such as slugs or snails) in its natural life cycle. Other animals that become infected such as freshwater shrimp, land crabs, frogs, and planarians of the genus Platydemus , are transport hosts that are not required for reproduction of the parasite but might be able to transmit infection to humans if eaten raw or undercooked. Humans are accidental hosts who do not transmit infection to others. Most cases of infection are diagnosed in Southeast Asia and the Pacific Basin, but the parasite has also been found in Australia, some areas of Africa, the Caribbean, Hawaii and Louisiana. Outbreaks of human rat lungworm have involved a few to hundreds of persons; over 2,800 cases have been reported in the literature from approximately 30 countries. It is likely that the parasite has been spread by rats transported on sh