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Risk of hemorrhage after childbirth high for women with hemophilia - Hemophilia News Today

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Women with hemophilia and other bleeding disorders are more likely to experience postpartum hemorrhage and other bleeding problems related to pregnancy and childbirth than those without such diseases, a population-based study from Canada reports. Findings "showed that women with inherited bleeding disorders are at increased odds of [postpartum hemorrhage] and antepartum haemorrhage [bleeding before childbirth] during pregnancy, and alarmingly high odds of severe [postpartum hemorrhage]," the researchers wrote. The study, " Impact of inherited bleeding disorders on maternal bleeding and other pregnancy outcomes: A population-based cohort study ," was published in the journal Haemophilia . Recommended Reading Although hemophilia is less common in women than men, it's known Postpartum hemorrhage — extensive blood loss following childbirth — is responsible for about 1 out of every 4 pregnancy-related deaths...

Von Willebrand Disease: Types, Symptoms, Causes, Diagnosis, Treatment and More - Health.com

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Von Willebrand disease (VWD) is the most common inherited bleeding disorder. The condition gets its name after Erik von Willebrand—a doctor who identified the disease in the 1920s. Your blood contains many proteins that help it clot properly and prevent excess blood loss. One of these proteins is called the "von Willebrand factor." This protein helps bind and clump with blood platelets, which are cell fragments in the blood that also help with clotting. When von Willebrand factor is present in your blood at low levels or if it's not working properly, you can experience heavy and frequent bleeding, like nosebleeds or abnormal menstrual bleeding. However, there are effective treatments available to manage the condition—and people who receive treatment can have healthy and active lives. There are four types of VWD and knowing what type you have is important. That's because each type has its own prognosis (outlook) and treatment plan. The types of VW...

Temperature, humidity may drive future transmission of parasitic worm infections - Penn State University

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UNIVERSITY PARK, Pa. — As climate changes, temperature isn't the only factor to influence the spread of infectious diseases. Humidity plays a role, too, according to new research published this week (Feb. 25) in Ecology Letters. The international team, led by Penn State researchers, developed a model to examine how parasitic worms, specifically species that infect livestock and wildlife, respond to changes in temperature and humidity and how those variables may shape the risk of infection and the development of new hot spots in the future. The findings, which may suggest similar behavior among worms that infect humans, could guide improvements in livestock management and public health interventions in endemic areas. "We need to understand how climate change can affect the future of these infections," said Isabella Cattadori, professor of biology at Penn State and senior author of the study. "Are they going to get worse? Are they going to shift into different habita...

Onchocerciasis - World Health Organization (WHO)

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Onchocerciasis – or "river blindness" – is a parasitic disease caused by the filarial worm Onchocerca volvulus transmitted by repeated bites of infected blackflies ( Simulium spp.). These blackflies breed along fast-flowing rivers and streams, close to remote villages located near fertile land where people rely on agriculture. In the human body, the adult worms produce embryonic larvae (microfilariae) that migrate to the skin, eyes and other organs. When a female blackfly bites an infected person during a blood meal, it also ingests microfilariae which develop further in the blackfly and are then transmitted to the next human host during subsequent bites. Clinical signs and symptoms Onchocerciasis is an eye and skin disease. Symptoms are caused by the microfilariae, which move around the human body in the subcutaneous tissue and induce intense inflammatory responses when they die. Infected people may show symptoms such as severe itching and various skin changes. Infecte...

Hemophilia A vs. B: What to know - Medical News Today

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Hemophilia A and B are similar conditions that affect the blood's ability to clot. They typically occur due to gene variations that affect different blood clotting factors. Hemophilia is a group of conditions that impact the blood's ability to coagulate, or clot. When the blood does not clot properly, a person is at a higher risk for spontaneous bleeding or severe bleeding following an injury. Hemophilia occurs when an individual has low levels of certain proteins in the blood, known as clotting factors. There are many different clotting factors, and they play an important role in the formation of blood clots. Hemophilia A and B are two of the most common types of hemophilia. Different types of hemophilia correspond to various clotting factors. Hemophilia A and B occur due to factor VIII and IX deficiencies, respectively. Hemophilia A and hemophilia B are the two main types of hemophilia. Both conditions have similarities but are distinguishable by the genetic variation that ca...

IDPH Health Regions & Local Health Departments - IDPH

At least sixteen Illinois cases are now linked to the reports of elevated lead levels in recalled cinnamon applesauce pouches. To learn more about the recall, go to https://www.cdc.gov/nceh/lead/news/lead-poisoning-outbreak-linked-to-cinnamon-applesauce-pouches.html. If you or a family member consumed this product, consult your health care provider. Adblock test (Why?)

Patients Often Lose in the Battle Between Pharmaceutical Companies and PBMs - Drug Topics

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Brooke Loving doesn't take the medication that would keep her von Willebrand disease under control. Because of the cost, she has made the decision to focus on treating her children instead: Loving and 3 of her 8 children have been diagnosed with von Willebrand disease, a bleeding disorder that is characterized by low levels of von Willebrand factor, a protein that helps blood clot. Two of Loving's children take Humate-P, a von Willebrand factor/factor VIII replacement therapy. It's expensive, but CSL Behring, the manufacturer of Humate-P, offers co-pay assistance of $10,000 a year. In previous years, Loving explained, they would use the co-pay card when it counted toward their out-of-pocket deductible. "When that ran out, our portion was about $300 a week," she said. But Blue Cross Blue Shield of Alabama, Loving's insurance company, and the pharmacy benefit manager (PBM) Express Scripts changed their policy and have implemented a program in which the co-pay as...